The OCF₃ group has good metabolic stability, suitable lipophilicity and special electrical properties, which can modify the properties of drugs and material molecules. In recent years, trifluoromethoxy compounds have received more and more attention. Both new reagents and new trifluoromethoxylation strategies got a breakthrough. Our group has been committed to the development of trifluoromethoxylation reagents and methods. This account focuses on describing various trifluoromethoxylation reactions with trifluoromethyl sulfonates (TFMS) and (E)‐O‐trifluoromethyl‐benzaldoximes (TFBO) developed by our group.

中文翻译：

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TFMS和TFBO三氟甲氧基化反应的最新进展

OCF ₃基团具有良好的代谢稳定性，适当的亲脂性和特殊的电学性质，可以改变药物和物质分子的性质。近年来，三氟甲氧基化合物受到越来越多的关注。新试剂和新的三氟甲氧基化策略都取得了突破。我们小组一直致力于开发三氟甲氧基化试剂和方法。该讲解着重描述了由我们小组开发的与三氟甲基磺酸盐（TFMS）和（E）-O-三氟甲基苯甲酰肟（TFBO）进行的各种三氟甲氧基化反应。