Catalytic Enantioselective Isocyanide‐Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions,Chemistry - A European Journal

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Catalytic Enantioselective Isocyanide‐Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2020-09-23 , DOI: 10.1002/chem.202003224
Jian Luo ₁ , Guo-Shu Chen ₁ , Shu-Jie Chen ₁ , Zhao-Dong Li ₂ , Yun-Lin Liu ₁

Affiliation

The development of catalytic enantioselective isocyanide‐based reactions is currently of great interest because the resulting products are valuable in organic synthesis, pharmacological chemistry, and materials science. This review assembles and comprehensively summarizes the recent achievements in this rapidly growing area according to the reaction types. Special attention is paid to the advantages, limitations, possible mechanisms, and synthetic applications of each reaction. In addition, a personal outlook on the opportunities for further exploration is given at the end.

中文翻译：

催化基于对映体选择性的异氰酸酯反应：超越Passerini和Ugi多组分反应

目前，基于对映体选择性的基于异氰酸酯的催化反应的研究引起了人们的极大兴趣，因为所得产物在有机合成，药理化学和材料科学中具有重要价值。这篇综述根据反应类型汇总并全面总结了这个快速增长领域中的最新成就。特别注意每个反应的优点，局限性，可能的机理和合成应用。此外，最后对进一步探索的机会提出了个人看法。

更新日期：2020-09-23

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