A simple, straightforward, and scalable procedure for the preparation of 2-bromofuran using N-bromosuccinimide (NBS) in dimethylformamide (DMF) is reported. The described preparation is conducted on a 20 to 50 g scale and does not require extractive workup procedures or chromatographic purifications. To illustrate the synthetic applications of 2-bromofuran, palladium-catalyzed Suzuki coupling reactions of the prepared 2-bromofuran with various aryl boronic acids were investigated, and moderate to good yields of 2-arylfurans were obtained.

中文翻译：

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2-溴呋喃的有效制备方法及其在2-芳基呋喃合成中的应用

报道了一种使用 N-溴代琥珀酰亚胺 (NBS) 在二甲基甲酰胺 (DMF) 中制备 2-溴呋喃的简单、直接且可扩展的程序。所述制备以 20 至 50 g 的规模进行，不需要萃取后处理程序或色谱纯化。为了说明 2-溴呋喃的合成应用，研究了制备的 2-溴呋喃与各种芳基硼酸的钯催化 Suzuki 偶联反应，并获得了中等至良好收率的 2-芳基呋喃。