ABSTRACT A new protocol has been developed for the efficient synthesis of structurally diverse N-cyclohexyl-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,5]diazepin-3-yl)-2-phenylacetamides through a one-pot, five-component condensation reaction of an aromatic diamine, an aromatic aldehyde, an isocyanide, ethyl malonyl chloride, and water in dichloromethane with good yields, at ambient temperature, in the presence of MgCl2 as a catalyst. GRAPHICAL ABSTRACT

中文翻译：

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基于一锅异氰化物的五组分反应：合成高度官能化的 N-环己基-2-(2,4-dioxo-2,3,4,5 四氢-1H-benzo[b][1,5]diazepin- 3-yl)-2-苯基乙酰胺

摘要开发了一种新的协议，用于有效合成结构多样的 N-环己基-2-(2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,5]diazepin- 3-基)-2-苯基乙酰胺通过芳香二胺、芳香醛、异氰化物、乙基丙二酰氯和水在二氯甲烷中的一锅五组分缩合反应，在室温下，在二氯甲烷存在下以良好的收率MgCl2 作为催化剂。图形概要