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Transition-metal-free synthesis of phenothiazines from S-2-acetamidophenyl ethanethioate and ortho-dihaloarenes
Synthetic Communications ( IF 1.8 ) Pub Date : 2017-02-23 , DOI: 10.1080/00397911.2017.1281959
Yue Zhou 1 , Qingle Zeng 1 , Li Zhang 1
Affiliation  

ABSTRACT An efficient cesium carbonate-mediated synthesis of phenothiazine derivatives from S-2-acetamidophenyl ethanethioates and ortho-dihaloarenes has been developed. This protocol affords an efficient approach for the construction of phenothiazine derivatives without the need of transition-metal catalyst or ligand. A plausible mechanism is proposed. GRAPHICAL ABSTRACT

中文翻译:

从 S-2-乙酰氨基苯基乙硫醚和邻二卤代芳烃无过渡金属合成吩噻嗪

摘要已开发出一种高效的碳酸铯介导的 S-2-乙酰氨基苯基乙硫醚和邻二卤代芳烃合成吩噻嗪衍生物。该协议提供了一种无需过渡金属催化剂或配体即可构建吩噻嗪衍生物的有效方法。提出了一个合理的机制。图形概要
更新日期:2017-02-23
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