当前位置: X-MOL 学术Synth. Commun. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
An alternative efficient approach for the synthesis of Fingolimod hydrochloride
Synthetic Communications ( IF 1.8 ) Pub Date : 2019-01-02 , DOI: 10.1080/00397911.2018.1536788
Krishna Vinigari 1, 2 , Krishna Jonnada 1 , Noorjahan Mohammed 2 , Girija Mangatayaru Kotu 2
Affiliation  

Abstract An efficient process for the synthesis of API Fingolimod Hydrochloride is presented. This proposed synthesis involves simple commercially available octanophenone as a starting material. The route is effective involving seven steps to achieve the target, thus reducing the cycle time, and is cost efficient by 50%. It is an immune modulating drug for the treatment of heart failure and arrhythmias. Graphical Abstract

中文翻译:

一种合成盐酸芬戈莫德的有效方法

摘要 提出了一种合成API 芬戈莫德盐酸盐的有效方法。该提议的合成涉及简单的市售辛苯酮作为起始材料。该路线是有效的,包括七个步骤来实现目标,从而减少周期时间,成本效率降低 50%。它是一种免疫调节药物,用于治疗心力衰竭和心律失常。图形概要
更新日期:2019-01-02
down
wechat
bug