ABSTRACT The dimethylated phenanthrenes 2,3-dimethylphenanthrene (4a), 2,7-dimethylphenanthrene (4b), 2,6-dimethylphenanthrene (4c) and 1,7-dimethylphenanthrene (4d) have been prepared in gram-quantities by a short sequence of directed ortho metalation (DoM) of N,N-diethylbenzamides followed by Suzuki–Miyaura cross-coupling reaction and directed remote metalation (DreM) to form 9-phenanthrols. The final phenanthrenes were obtained through protection/deprotection as triflates.

中文翻译：

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二甲基菲的区域特异性合成

摘要 通过短序列制备了克量的二甲基化菲 2,3-二甲基菲 (4a)、2,7-二甲基菲 (4b)、2,6-二甲基菲 (4c) 和 1,7-二甲基菲 (4d) N,N-二乙基苯甲酰胺的定向邻位金属化 (DoM)，然后是 Suzuki-Miyaura 交叉偶联反应和定向远程金属化 (DreM) 以形成 9-菲酚。最终菲以三氟甲磺酸酯的形式通过保护/脱保护获得。