An easy, solvent-free method for the synthesis of 1-(4-chlorophenyl)pyrazolidin-3-one has been achieved by grinding 4-chlorophenyl hydrazine and methyl acrylate in the presence of base in a ball mill. A systematic investigation of the reaction has been made in order to study the various factors affecting the reaction.

中文翻译：

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球磨机中无溶剂合成1-（4-氯苯基）吡唑烷-3-

通过在球磨机中在碱的存在下研磨4-氯苯基肼和丙烯酸甲酯，已经实现了一种简单，无溶剂的合成1-（4-氯苯基）吡唑烷丁-3-酮的方法。为了研究影响反应的各种因素，已经对该反应进行了系统的研究。