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A New Fluorescent Probe for Selective Cd2+ Detection and Cell Imaging
Zeitschrift für anorganische und allgemeine Chemie ( IF 1.1 ) Pub Date : 2019-03-19 , DOI: 10.1002/zaac.201800454
Wenxin Lin 1 , Xiaochun Xie 1 , Yijia Wang 1 , Jianjun Chen 1
Affiliation  

A new highly selective fluorescent probe, (E)‐4‐(4‐([2,2′:6′,2′′‐terpyridin]‐4′‐yl)styryl)‐1‐octadecylpyridin‐1‐ium bromide (ZC‐F8), was designed and synthesized for cadmium detection and cell imaging. The fluorescence spectra of ZC‐F8 exhibited its excellent response towards Cd2+ via intramolecular charge transfer effect and aggregation induced emission effect. The cell‐imaging experiment was carried out to estimate the actual biological application of ZC‐F8. The probe displayed ideal membrane permeable and labeled property for cadmium, indicating its promising application for metal ions detection and tracing in living cells.

中文翻译:

一种用于选择性Cd2 +检测和细胞成像的新型荧光探针

一种新的高选择性荧光探针(E)-4-(4-([[2,2':6',2''-terpyridin] -4-4'-yl)styryl)-1-十八烷基吡啶-1-溴化铵( ZC-F8)是为镉检测和细胞成像而设计和合成的。ZC-F8的荧光光谱通过分子内电荷转移效应和聚集诱导的发射效应表现出对Cd 2+的出色响应。进行细胞成像实验以评估ZC-F8的实际生物学应用。该探针对镉显示出理想的膜渗透性和标记特性,表明其在活细胞中金属离子检测和示踪方面的应用前景广阔。
更新日期:2019-03-19
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