Transparent hydroxyapatite/citric acid (Cit/HA) particulate film formation and the stability in biological solution were investigated. Negatively charged Cit/HA nanoparticles were synthesized, and the particulate films were prepared by a spin-coat method through water or ethanol dispersion. As a result, the crack-free and transparent Cit/HA films were prepared from water dispersion, which exhibited the better optical properties as compared with the films prepared from ethanol dispersion. The Cit/HA films exhibited higher optical transmittance with increasing the hybridized Cit amount, and the highest transmittance in the visible light region exceeded 80%. Moreover, the calcined film had long-term stability in phosphate-buffered saline while maintaining high transparency, which is expected to be used as a candidate coating film for cell culture substrates.

研究了透明羟基磷灰石/柠檬酸（Cit / HA）颗粒膜的形成以及在生物溶液中的稳定性。合成带负电荷的Cit / HA纳米粒子，并通过旋涂法通过水或乙醇分散液制备颗粒膜。结果，由水分散体制备无裂纹且透明的Cit / HA膜，与由乙醇分散体制备的膜相比，其显示出更好的光学性质。随着杂化Cit量的增加，Cit / HA膜表现出更高的透光率，可见光区的最高透光率超过80％。此外，煅烧后的薄膜在磷酸盐缓冲液中具有长期稳定性，同时保持高透明度，