Excessive use of organophosphorus pesticides such as pyridaphenthion (PY) to constrain insects induced crop loss, results in soil and water sources contamination. Cyanobacteria are sensitive biological indicators and promising tools for bioremediation of soil and water pollutants. To understand PY toxicity, detoxification and degradation in cyanobacteria, we performed a comparative study in the two diazotrophic cyanobacteria; Anabaena laxa and Nostoc muscorum. They were exposed to mild (5 mg/L) and high (10 mg/L) concentrations of PY for 7 days. Compared to A. laxa, N. muscorum efficiently showed high PY accumulation and degradation to a safe environmentally product; 6-hydroxy-2-phenylpyridazin-3(2 H)-one. PY inhibited cell growth and reduced Chl a content and photosynthesis related enzymes (PEPC and RuBisCo) activities in both species, but to less extend in N. muscorum. It also induced oxidative damage, particularly in A. laxa, as indicated by high H₂O₂, lipid peroxidation and protein oxidation levels and increased NADPH oxidase enzyme activity. N. muscorum invested more in antioxidants induction, i.e., induced ascorbate and glutathione cycle, however, these antioxidants increments in A. laxa were less pronounced. Overall, this study provides more in-deep insights into the PY toxicity and the role of N. muscorum as a promising PY remediator.

过量使用有机磷杀虫剂，例如哒嗪磷（PY）来抑制昆虫引起的农作物损失，导致土壤和水源受到污染。蓝细菌是敏感的生物指标，是土壤和水污染物进行生物修复的有前途的工具。为了了解蓝细菌的PY毒性，排毒和降解，我们对两种重氮营养蓝细菌进行了比较研究。疏花鱼腥藻和念珠藻muscorum。他们暴露于轻度（5 mg / L）和高浓度（10 mg / L）的PY中7天。与松果油菌相比，粘液猪油菌显示出高的PY积累和降解，成为安全的环境产品；6-羟基-2-苯基哒嗪-3（2 H）-1。PY抑制细胞生长并降低Chl两种物种的含量和与光合作用相关的酶（PEPC和RuBisCo）的活性，但在粘液猪笼草中却很少。它也引起氧化损伤，特别是在A. laxa中，表现为高H ₂ O ₂，脂质过氧化和蛋白质氧化水平以及增加的NADPH氧化酶活性。N. muscorum抗氧化剂感应，投入即引起抗坏血酸和谷胱甘肽周期，然而，在这些抗氧化剂的增量A.疏花了不太明显。总体而言，这项研究提供了对PY毒性和粘液猪笼草作为有前途的PY修复剂的作用的更深入的见解。