Conjugated-Polymer-Based Nanomaterials for Photothermal Therapy,ACS Applied Polymer Materials

当前位置： X-MOL 学术 › ACS Appl. Polym. Mater. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Conjugated-Polymer-Based Nanomaterials for Photothermal Therapy
ACS Applied Polymer Materials ( IF 4.4 ) Pub Date : 2020-08-31 , DOI: 10.1021/acsapm.0c00680
Yufei Wang ₁ , Hong-Min Meng ₁ , Guosheng Song ₂ , Zhaohui Li ₁ , Xiao-Bing Zhang ₂

Affiliation

In the past few decades, the development of excellent materials for the treatment of disease via noninvasive photothermal therapy has received increasing attention. Among a number of kinds of nanomaterials, conjugated-polymer-based nanomaterials, which possess intense absorbance in the near-infrared region, could employed as useful photothermal agents for various disease treatments, such as cancer, bacterial infection therapy, and neurodegenerative disease. Moreover, conjugated-polymer-based nanomaterials can be easily combined with other imaging agents and drugs to construct multifunctional nanomaterials for cascading stimuli-responsiveness with precise medical treatment and enhanced therapy efficacy. Here, we mainly put attention on the recent advances of conjugated-polymer-based nanoparticles for photothermal therapy. First, we briefly summarized the mechanism of photothermal conversion of conjugated polymers and the relevant modified methods to improve their photothermal conversion efficiency. Second, we discussed the application of conjugated polymers in photothermal therapy as well as the strategies for developing conjugated-polymer-based nanomaterials with a targeted ability and an enhanced accumulation effect on the tumor region for cancer therapy. Moreover, further challenges and perspectives were also discussed for designing efficient conjugated-polymer-based nanosystems for photothermally assisted therapies.

中文翻译：

基于共轭聚合物的纳米材料用于光热疗法

在过去的几十年中，通过无创光热疗法治疗疾病的优良材料的开发受到越来越多的关注。在许多种类的纳米材料中，在近红外区域具有强吸收性的基于共轭聚合物的纳米材料可以用作有用的光热剂，用于各种疾病治疗，例如癌症，细菌感染治疗和神经退行性疾病。此外，基于共轭聚合物的纳米材料可以轻松地与其他显像剂和药物组合，以构建多功能纳米材料，从而在精确的医学治疗和增强的治疗效果之间实现级联的刺激反应性。在这里，我们主要关注基于共轭聚合物的纳米粒子用于光热疗法的最新进展。第一，我们简要总结了共轭聚合物的光热转化机理以及改进其光热转化效率的相关改进方法。其次，我们讨论了共轭聚合物在光热疗法中的应用，以及开发基于共轭聚合物的纳米材料的策略，该纳米材料具有针对性和对肿瘤区域的增强的肿瘤治疗效果。此外，还讨论了为光热辅助疗法设计有效的基于共轭聚合物的纳米系统的其他挑战和前景。我们讨论了共轭聚合物在光热疗法中的应用，以及开发基于共轭聚合物的纳米材料的策略，该纳米材料具有针对性和对肿瘤区域的增强的肿瘤治疗效果。此外，还讨论了为光热辅助疗法设计有效的基于共轭聚合物的纳米系统的其他挑战和前景。我们讨论了共轭聚合物在光热疗法中的应用，以及开发具有靶向能力和增强的对肿瘤区域的肿瘤治疗效果的基于共轭聚合物的纳米材料的策略。此外，还讨论了为光热辅助疗法设计有效的基于共轭聚合物的纳米系统的其他挑战和前景。

更新日期：2020-10-11

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南