Synthetic elicitors are drug-like compounds that are structurally distinct from natural defense elicitors. They can protect plants from diseases by activating host immune responses and can serve as tools for the dissection of the plant immune system as well as leads for the development of environmentally-safe pesticide alternatives. By high-throughput screening, we previously identified 114 synthetic elicitors that activate expression of the pathogen-responsive CaBP22(-333)::GUS reporter gene in Arabidopsis thaliana (Arabidopsis), 33 of which are [(phenylimino)methyl]phenol (PMP) derivatives or PMP-related compounds. Here we report on the characterization of one of these compounds, 2,4-dichloro-6-{(E)-[(3-methoxyphenyl)imino]methyl}phenol (DPMP). DPMP strongly triggers disease resistance of Arabidopsis against bacterial and oomycete pathogens. By mRNA-seq analysis we found transcriptional profiles triggered by DPMP to resemble typical defense-related responses.

中文翻译：

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合成诱导剂DPMP（2,4-二氯-6-{（E）-[（3-甲氧基苯基）亚氨基]甲基}苯酚）在拟南芥和番茄中引发较强的免疫力。

合成激发子是类似于药物的化合物，其结构与天然防御激发子不同。它们可以通过激活宿主的免疫反应来保护植物免受疾病侵害，并且可以作为解剖植物免疫系统的工具以及开发对环境安全的农药替代品的先导。通过高通量筛选，我们先前鉴定了114个合成激发子，这些合成激发子可激活拟南芥（Arabidopsis）中病原体响应性CaBP22（-333）:: GUS报告基因的表达，其中33个为[（苯基亚氨基）甲基]苯酚（PMP） ）衍生物或与PMP相关的化合物。在这里，我们报告这些化合物之一，2,4-二氯-6-{（E）-[（3-甲氧基苯基）亚氨基]甲基}苯酚（DPMP）的表征。DPMP强烈触发拟南芥对细菌和卵菌病原体的抗病性。