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Transformations of 1-phenethyl-1,2,3,6-tetrahydropyridines in the presence of trifluoromethanesulfonic acid
Chemistry of Heterocyclic Compounds ( IF 1.4 ) Pub Date : 2020-08-22 , DOI: 10.1007/s10593-020-02748-8
Vera A. Shadrikova , Alexander S. Popov , Maria V. Termelyova , Marat R. Baimuratov , Yuri N. Klimochkin

1-Phenethyl-1,2,3,6-tetrahydropyridines undergo intramolecular Friedel–Crafts reaction in trifluoromethanesulfonic acid medium, resulting in the formation of azatricyclic structures. It was shown that the direction of this reaction depended on the position of the substituent relative to the multiple bond in tetrahydropyridine. The structures of the obtained compounds were confirmed by a set of spectral analysis methods.


中文翻译:

在三氟甲磺酸存在下1-苯乙基-1,2,3,6-四氢吡啶的转化

1-苯乙基1,2,3,6-四氢吡啶在三氟甲磺酸介质中进行分子内Friedel-Crafts反应,形成氮杂三环结构。结果表明,该反应的方向取决于取代基相对于四氢吡啶中多键的位置。所得化合物的结构通过一套光谱分析方法确认。
更新日期:2020-08-22
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