Abstract A synthesis of novel bis(benzo[4,5]imidazo[1,2-a]pyridines) via the reaction of the appropriate bis(aldehyde) with 2-(1H-benzo[d]imidazol-2-yl)acetonitrile and malononitrile in ethanol at reflux in the presence of piperidine was reported. On the other hand, attempted synthesis of bis(benzo[4,5]thiazolo[3,2-a]pyridines) by a three-component reaction of the appropriate bis-aldehyde with malononitrile and (benzo[d]thiazol-2-yl)acetonitrile under similar reaction conditions was unsuccessful. The reactions gave instead the corresponding novel bis(benzo[d]thiazol-2-yl)acrylonitriles. Graphical Abstract

中文翻译：

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(1H-苯并[d]咪唑-2-基)乙腈和(苯并[d]噻唑-2-基)乙腈作为新型双(苯并[4,5]咪唑[1,2-基)前体的反应性研究a]吡啶）和双（苯并[4,5]噻唑并[3,2-a]吡啶）

摘要 通过合适的双（醛）与 2-（1H-苯并[d]咪唑-2-基）乙腈反应合成新型双（苯并[4,5]咪唑并[1,2-a]吡啶）据报道，丙二腈在乙醇中在哌啶存在下回流。另一方面，通过适当的双醛与丙二腈和（苯并[4,5]噻唑并[3,2-a]吡啶）的三组分反应，尝试合成双（苯并[4,5]噻唑并[3,2-a]吡啶）。 yl)乙腈在类似反应条件下未成功。该反应产生了相应的新型双(苯并[d]噻唑-2-基)丙烯腈。图形概要