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Alginate hydrogel dressings for advanced wound management.
International Journal of Biological Macromolecules ( IF 7.7 ) Pub Date : 2020-08-07 , DOI: 10.1016/j.ijbiomac.2020.07.311
Miao Zhang 1 , Xia Zhao 1
Affiliation  

Wound healing is a complicated and continuous process affected by several factors, and it needs an appropriate surrounding to achieve accelerated healing. At present, various wound dressings are used for wound management, such as fiber, sponge, hydrogel, foam, hydrocolloid and so on. Hydrogels can provide mechanical support and moist environment for wounds, and are widely used in biomedical field. Alginate is a natural linear polysaccharide derived from brown algae or bacteria, consisting of repeating units of β-1,4-linked D-mannuronic acid (M) and L-guluronic acid (G) in different ratios. It is widely used in biomedical and engineering fields due to its good biocompatibility and liquid absorption capacity. Alginate-based hydrogels have been used in wound dressing, tissue engineering, and drug delivery applications for decades. In this review, we summarize the recent approaches in the chemical and physical preparation and the application of alginate hydrogels in wound dressings.



中文翻译:

海藻酸盐水凝胶敷料,用于高级伤口处理。

伤口愈合是一个复杂且持续的过程,受多个因素影响,并且需要适当的环境来加速愈合。目前,各种伤口敷料用于伤口处理,例如纤维,海绵,水凝胶,泡沫,水胶体等。水凝胶可以为伤口提供机械支撑和湿润的环境,并广泛用于生物医学领域。海藻酸盐是衍生自褐藻或细菌的天然线性多糖,由β-1,4-连接的D-甘露糖醛酸(M)和L-古洛糖醛酸(G)的不同比例的重复单元组成。由于其良好的生物相容性和液体吸收能力,它被广泛用于生物医学和工程领域。基于藻酸盐的水凝胶已经在伤口敷料,组织工程和药物递送应用中使用了数十年。在这篇评论中

更新日期:2020-08-08
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