In electrochemiluminescence sensing platforms, co-reaction accelerators are specific materials used to catalyze the dissociation of co-reactants into active radicals, which can significantly boost the ECL emission of luminophores. Deep insight into the correlation between the structure and ECL performance will guide the rational design of highly active co-reaction accelerators, which is imperative for constructing sensitive and reliable ECL biosensors. In this review, a brief introduction about the basic ECL mechanisms based on the co-reactant pathway is presented. After that, recent developments with various co-reaction accelerators are further discussed regarding different luminophore systems, including luminol, g-C₃N₄, quantum dots, nanoclusters and others. Furthermore, synergistic amplification strategies based on efficient co-reaction accelerators and enzyme immune and hybrid chain reactions are elucidated. Finally, the outlook for the preparation of high-performance ECL sensors with efficient co-reaction accelerators is discussed as well.

中文翻译：

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用于敏感电化学发光分析的共反应促进剂的最新进展。

在电化学发光传感平台中，共反应促进剂是用于催化共反应物分解为活性基团的特殊材料，可显着提高发光体的ECL发射。对结构与ECL性能之间关系的深入了解将指导高活性共反应促进剂的合理设计，这对于构建灵敏可靠的ECL生物传感器至关重要。在这篇综述中，简要介绍了基于共反应物途径的基本ECL机制。之后，针对各种发光体系统（包括鲁米诺，gC ₃ N _4）进一步讨论了各种共反应促进剂的最新发展。，量子点，纳米簇等。此外，阐明了基于有效的共反应促进剂和酶免疫和杂合链反应的协同扩增策略。最后，还讨论了使用高效的共反应促进剂制备高性能ECL传感器的前景。