The [1,2,4]triazolo[1,5-a]pyrimidines (TPs) comprise an important class of non-naturally occurring small molecules that aroused the interest of researches. This scaffold is present in diverse important structures in agriculture and medicinal chemistry, such as antibacterial, antifungal, antiviral, antiparasitic, and anticancer. As over the decades the development of the chemistry and application of 1,2,4-triazolo[1,5-a]pyrimidines has continued and even accelerated, in this review, we thoroughly discussed the applications of TPs in both agriculture and medicinal chemistry highlighting the significance of this nucleus.

中文翻译：

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[1,2,4]三唑并[1,5-a]嘧啶及其类似物的生物活性

[1,2,4]三唑并[1,5- a ]嘧啶（TPs）包含一类重要的非天然小分子，引起了人们的研究兴趣。该支架存在于农业和药物化学的各种重要结构中，例如抗菌，抗真菌，抗病毒，抗寄生虫和抗癌。几十年来，随着化学的发展和1,2,4-三唑并[1,5- a ]嘧啶的应用不断发展，甚至在加速，在本综述中，我们彻底讨论了TP在农业和药物化学中的应用突出了这个核的意义。