Using a sulfated polysaccharide from the gonad of pacific abalone (AGSP), a novel polysaccharide-Fe(III) complex, AGSP-Fe(III), was synthesized, and it was characterized by a series of methods including ultraviolet-visible (UV–vis) spectroscopy, Fourier transform-infrared (FT-IR) spectroscopy, circular dichroism (CD) spectroscopy, scanning electron microscopy (SEM), and atomic force microscopy (AFM). The results showed that AGSP-Fe(III) was formed by the Fe-O bond between sulfate, carboxyl, and hydroxyl groups in AGSP and Fe, its particle size reached a maximum of 200 nm after aggregating, and its surface morphology presented relatively regular columnar or spherical. Moreover, the iron release of AGSP-Fe(III) during simulated gastrointestinal digestion was exhibited, and its good iron supplementary efficiency was also shown using Caco-2 cells. In addition, compared to FeCl₃, AGSP-Fe(III) showed better solubility and stability in the presence of polyphenol/trypsin. The present study demonstrated the potential of AGSP-Fe(III) as a novel iron supplement.

利用来自太平洋鲍鱼性腺（AGSP）的硫酸化多糖，合成了一种新型的多糖-Fe（III）复合物AGSP-Fe（III），并通过包括紫外可见（UV-可见光谱，傅里叶变换红外（FT-IR）光谱，圆二色性（CD）光谱，扫描电子显微镜（SEM）和原子力显微镜（AFM）。结果表明，AGSP-Fe（III）由AGSP和Fe中的硫酸根，羧基和羟基之间的Fe-O键形成，聚集后粒径最大为200 nm，表面形貌相对规则。柱状或球形。此外，在模拟胃肠消化过程中，AGSP-Fe（III）释放出铁，并使用Caco-2细胞显示出良好的铁补充效率。_{如图3所示}，在多酚/胰蛋白酶的存在下，AGSP-Fe（III）显示出更好的溶解性和稳定性。本研究证明了AGSP-Fe（III）作为新型铁补充剂的潜力。