Detergent‐Like Polymerizable Monomers: Synthesis, Physicochemical, and Biochemical Characterization,European Journal of Organic Chemistry

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Detergent‐Like Polymerizable Monomers: Synthesis, Physicochemical, and Biochemical Characterization
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-07-15 , DOI: 10.1002/ejoc.202000540
Christophe Bonnet ₁ , Pierre Guillet ₁ , Florian Mahler ₂ , Sébastien Igonet ₃ , Sandro Keller ₂ , Anass Jawhari ₃ , Gregory Durand ₄

Affiliation

Surfmers were synthesized and were found to be able to self‐assemble in water into micelles of ca. 6 nm in diameter at a critical micellar concentration that depends on the length of the alkyl chain. They were found to solubilize phospholipid vesicles and to extract a broad range of proteins from Escherichia coli membranes as well as the human adenosine receptor A_2AR and the bacterial transporter AcrB.