Introduction and hypothesis The paucity of long-term safety and efficacy data to support laparoscopic mesh sacrohysteropexy is noteworthy given concerns about the use of polypropylene mesh in pelvic floor surgery. This study is aimed at determining the incidence of mesh-associated complications and reoperation following this procedure. Methods This was a cross-sectional postal questionnaire study of women who underwent laparoscopic mesh sacrohysteropexy between 2010 and 2018. Potential participants were identified from surgical databases of five surgeons at two tertiary urogynaecology centres in the UK. The primary outcome was patient-reported mesh complication requiring removal of hysteropexy mesh. Secondary outcomes included other mesh-associated complications, reoperation rates and Patient Global Impression of Improvement (PGI-I) in prolapse symptoms. Descriptive statistics and Kaplan–Meier survival analyses were used. Results Of 1,766 eligible participants, 1,121 women responded (response proportion 63.5%), at a median follow-up of 46 months. The incidence of mesh complications requiring removal of hysteropexy mesh was 0.4% (4 out of 1,121). The rate of chronic pain service use was 1.8%, and newly diagnosed systemic autoimmune disorders was 5.8%. The rate of reoperation for apical prolapse was 3.7%, and for any form of pelvic organ prolapse it was 13.6%. For PGI-I, 81.4% of patients were “much better” or “very much better”. Conclusions Laparoscopic mesh sacrohysteropexy has a low incidence of reoperation for mesh complications and apical prolapse, and a high rate of patient-reported improvement in prolapse symptoms. With appropriate clinical governance measures, the procedure offers an alternative to vaginal hysterectomy with apical suspension. However, long-term comparative studies are still required.

中文翻译：

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腹腔镜网片骶骨子宫固定术后的长期补片并发症和再次手术：横断面研究

引言和假设 考虑到对在盆底手术中使用聚丙烯网片的担忧，支持腹腔镜网片骶骨子宫固定术的长期安全性和有效性数据的缺乏值得注意。本研究旨在确定该手术后补片相关并发症和再次手术的发生率。方法 这是一项对 2010 年至 2018 年间接受腹腔镜网状骶骨子宫固定术的女性进行的横断面邮寄问卷调查。潜在参与者是从英国两个三级泌尿妇科中心的五位外科医生的外科数据库中确定的。主要结果是患者报告的需要移除子宫固定网的网片并发症。次要结果包括其他网格相关并发症，脱垂症状的再手术率和患者总体改善印象 (PGI-I)。使用描述性统计和 Kaplan-Meier 生存分析。结果 在 1,766 名符合条件的参与者中，1,121 名女性做出了回应（回应比例为 63.5%），中位随访时间为 46 个月。需要去除子宫固定网的补片并发症的发生率为 0.4%（1,121 人中有 4 人）。慢性疼痛服务使用率为1.8%，新诊断全身性自身免疫性疾病为5.8%。根尖脱垂的再手术率为3.7%，任何形式的盆腔器官脱垂的再手术率为13.6%。对于 PGI-I，81.4% 的患者“好多了”或“好多了”。结论 腹腔镜下骶骨固定术因补片并发症和根尖脱垂再次手术的发生率低，患者报告的脱垂症状改善率很高。通过适当的临床管理措施，该程序提供了一种替代阴道子宫切除术和根尖悬吊术的方法。然而，仍然需要长期的比较研究。