Abstract Nanotechnology is an embryonic field that grips countless impacts on the drug delivery system. Nanoparticles as haulers increase the capability of target-specific drug delivery to many folds hence are used in the treatment of dreadful diseases such as cancer, diabetes, etc. This boom has aimed at, to synthesize Copper oxide nanoparticles (CuO-NPs) using Acalypha Indica leaf extract and then incorporated with graphene oxide (GO) to form GO-CuO nanocomposites. Secondly, to sightsee the photocatalytic activity of CuO-NPs and GO-CuO nanocomposites towards the decolorization of methylene blue-dye and to test its activity against HCT-116 Human colon cancer cell lines. Synthesized nanocomposites were characterized using FTIR, UV–vis, X-ray powder diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDAX), X-ray Photoelectron Spectroscopy (XPS) and transmission electron microscopy (TEM) analysis. The photocatalytic studies revealed that synthesized nanocomposites have the efficiency to degrade methylene blue dye by 83.20% and cytotoxic activity was found to be 70% against HCT-116 Human colon cancer cell lines at 100 μg/ml. GO-CuO nanocomposites have appreciable activity towards cancer cell lines and photocatalytic activity when compared to nanoparticles as such.

中文翻译：

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绿色合成用氧化石墨烯修饰的氧化铜纳米粒子的抗癌活性和催化应用

摘要 纳米技术是一个胚胎领域，对药物输送系统产生无数影响。作为运输工具的纳米颗粒将靶向特定药物的输送能力提高了许多倍，因此被用于治疗可怕的疾病，如癌症、糖尿病等。 这种热潮旨在使用 Acalypha 合成氧化铜纳米颗粒 (CuO-NPs)籼叶提取物，然后与氧化石墨烯 (GO) 结合形成 GO-CuO 纳米复合材料。其次，观察CuO-NPs和GO-CuO纳米复合材料对亚甲基蓝染料脱色的光催化活性，并测试其对HCT-116人结肠癌细胞系的活性。合成的纳米复合材料使用 FTIR、UV-vis、X 射线粉末衍射 (XRD)、扫描电子显微镜 (SEM)、能量色散 X 射线分析 (EDAX)、X 射线光电子能谱 (XPS) 和透射电子显微镜 (TEM) 分析。光催化研究表明，合成的纳米复合材料具有 83.20% 的降解亚甲基蓝染料的效率，并且发现对 HCT-116 人结肠癌细胞系的细胞毒活性为 70%，浓度为 100 μg/ml。与纳米颗粒相比，GO-CuO 纳米复合材料对癌细胞系具有可观的活性和光催化活性。