We propose a simple and inexpensive SiO₂ submicron particle synthesis method based on a PTFE helical capillary microreactor. The device is based on Dean flow mediated, ultrafast mixing of two liquid phases in a microfluidic spiral pipe. Excellent control of particle size between 100 nm and 600 nm and narrow polydispersity can be achieved by controlling the device and process parameters. Numerical simulations are performed to determine the optimal device dimensions. In the mother liquor the silica particles exhibit zeta potentials < −60 mV, rendering them very stable even at high particle volume fractions. The current device typically produces around 0.234 g/h of the silica particles.

我们提出了一种基于PTFE螺旋毛细管微反应器的简单且廉价的SiO ₂亚微米颗粒合成方法。该设备基于Dean流介导的微流体螺旋管中两种液相的超快混合。通过控制设备和工艺参数，可以很好地控制100 nm至600 nm之间的粒径以及窄的多分散性。进行数值模拟以确定最佳的器件尺寸。在母液中，二氧化硅颗粒表现出<-60 mV的zeta电位，即使在高颗粒体积分数下，它们也非常稳定。当前装置通常产生约0.234g / h的二氧化硅颗粒。