Postural tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance associated with cognitive dysfunction. We hypothesized executive function and attention is impaired in POTS during active standing. Eighty-seven POTS participants and 39 healthy controls of similar age, sex, and education level completed executive function (Stroop word-color) and attention (CogState Identification) tests in supine and standing postures in a cross-sectional study. POTS participants had lower executive function (t-score: 48 ± 11 vs. 55 ± 10 control; p = 0.009) and worse attention (reaction speed: 2.78 ± 0.11 vs. 2.69 ± 0.06 control; p < 0.001) during standing. These data provide new evidence that active standing impairs attention and executive functioning in POTS.

中文翻译：

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体位性心动过速综合征患者主动站立时注意力和执行功能受损

姿势性心动过速综合征 (POTS) 是一种与认知功能障碍相关的慢性直立不耐受形式。我们假设在主动站立期间 POTS 的执行功能和注意力受损。在横断面研究中，87 名 POTS 参与者和 39 名年龄、性别和教育水平相近的健康对照完成了仰卧和站立姿势的执行功能（Stroop word-color）和注意力（CogState Identification）测试。POTS 参与者在站立期间的执行功能较低（t 分数：48 ± 11 与 55 ± 10 对照；p = 0.009）和较差的注意力（反应速度：2.78 ± 0.11 与 2.69 ± 0.06 对照；p < 0.001）。这些数据提供了新的证据，表明主动站立会损害 POTS 的注意力和执行功能。