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A glass nanopore ionic sensor for surface charge analysis
RSC Advances ( IF 3.9 ) Pub Date : 2020-6-5 , DOI: 10.1039/d0ra03353g Songyue Chen 1 , Hong Chen 2 , Jian Zhang 3 , Hepeng Dong 1 , Kan Zhan 3 , Yongliang Tang 1
RSC Advances ( IF 3.9 ) Pub Date : 2020-6-5 , DOI: 10.1039/d0ra03353g Songyue Chen 1 , Hong Chen 2 , Jian Zhang 3 , Hepeng Dong 1 , Kan Zhan 3 , Yongliang Tang 1
Affiliation
Surface charge-based nanopore characterization techniques unfold unique properties and provide a powerful platform for a variety of sensing applications. In this paper, we have proposed a nanoconfined inner wall surface charge characterization method with glass nanopores. The glass nanopores were functionalized with DNA aptamers that were designed for mercury (Hg2+) ion immobilization by forming thymine–Hg2+–thymine structures. The surface charge of the nanopores was modulated by surface chemistry and Hg2+ ion concentrations and analysed by combining zeta potential measurements on glass slides and the ionic current rectification ratio of the nanopores. Also, 1 pM Hg2+ ions could be detected by the nanopores.
中文翻译:
用于表面电荷分析的玻璃纳米孔离子传感器
基于表面电荷的纳米孔表征技术展现了独特的特性,并为各种传感应用提供了强大的平台。在本文中,我们提出了一种具有玻璃纳米孔的纳米限制内壁表面电荷表征方法。玻璃纳米孔用设计用于通过形成胸腺嘧啶-Hg 2+ -胸腺嘧啶结构来固定汞(Hg 2+ )离子的DNA适体进行功能化。纳米孔的表面电荷通过表面化学和 Hg 2+离子浓度进行调节,并通过结合载玻片上的 zeta 电位测量和纳米孔的离子电流整流比进行分析。此外,纳米孔可以检测到1 pM Hg 2+离子。
更新日期:2020-06-05
中文翻译:
用于表面电荷分析的玻璃纳米孔离子传感器
基于表面电荷的纳米孔表征技术展现了独特的特性,并为各种传感应用提供了强大的平台。在本文中,我们提出了一种具有玻璃纳米孔的纳米限制内壁表面电荷表征方法。玻璃纳米孔用设计用于通过形成胸腺嘧啶-Hg 2+ -胸腺嘧啶结构来固定汞(Hg 2+ )离子的DNA适体进行功能化。纳米孔的表面电荷通过表面化学和 Hg 2+离子浓度进行调节,并通过结合载玻片上的 zeta 电位测量和纳米孔的离子电流整流比进行分析。此外,纳米孔可以检测到1 pM Hg 2+离子。