Despite being one of the most widely used fungicides in the agricultural industry, iprodione is a known water pollutant, and its continuous release into water sources is detrimental to human health. In this study, sensitive molecularly imprinted quartz crystal microbalance (MIP–QCM) sensors were prepared by fabricating two types of frisbee-like pillar patterns (MIP-3 μm and MIP-5 μm) onto the surface of gold quartz crystals for the real-time detection of iprodione in aqueous solutions. This study describes the synthesis of iprodione-imprinted poly(methacrylic acid-co-2-(trifluoromethyl)acrylic acid-co-ethylene glycol dimethacrylate), referred to as poly(MAA–co–TFMAA–co–EGDMA), in combination with a micro-contact printing technique (μ-CP), via ultraviolet (UV)-assisted photopolymerization. The patterned surfaces with increased surface-to-volume (S/V) ratio were characterized via atomic force microscopy (AFM), scanning force microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). The planar imprinted films and the corresponding non-imprinted films were prepared as the control samples for evaluating the sensor’s detection capabilities. According to the results, the MIP–QCM sensors had enhanced detection capabilities compared to their planar MIP counterparts owing to the increased binding affinity on the structured surfaces. The imprinting factor (IF) (i.e., Q_e,MIP/Q_e,NIP) indicated that the imprinting effects for each MIP film was comparatively assessed, resulting in the following order: 1.69 (MIP-plane) <2.21 (MIP-5 μm) <2.74 (MIP-3 μm). The LOQ and LOD values were 54.407 and 17.954 nM⁻¹ (MIP-plane), 24.624 and 8.126 nM⁻¹ (MIP-5 μm), and 62.423 and 20.600 nM⁻¹ (MIP-3 μm). The binding affinity of the iprodione MIP films was evaluated using the Freundlich isotherm model, and the template amount detected in an iprodione aqueous solution ranged between 30 and 303 nM. Furthermore, the selectivity of the patterned MIP films for iprodione detection was also investigated in aqueous solutions in the presence of two other fungicides: pyrimethanil and procymidone.

尽管异丙嗪酮是农业工业中使用最广泛的杀真菌剂之一，但它还是一种已知的水污染物，其持续释放到水源中对人体健康有害。在这项研究中，通过在金石英晶体表面上制作两种类型的飞盘状柱状图案（MIP-3μm和MIP-5μm）来制备敏感的分子印迹石英晶体微天平（MIP–QCM）传感器，以实现水溶液中异丙洛酮的时间检测。这项研究描述了异丙隆印记的聚（甲基丙烯酸-co-2-（三氟甲基）丙烯酸-乙二醇二甲基丙烯酸乙酯），与聚（MAA-co-TFMAA-co-EGDMA）的合成通过紫外线（UV）辅助光聚合的微接触印刷技术（μ-CP）。通过原子力显微镜（AFM），扫描力显微镜（SEM）和傅里叶变换红外光谱（FTIR）对具有增加的表面体积（S / V）比的图案化表面进行了表征。准备平面压印膜和相应的非压印膜作为对照样品，以评估传感器的检测能力。根据结果​​，由于其在结构化表面上的结合亲和力增强，与平面MIP传感器相比，MIP-QCM传感器具有增强的检测能力。印记因子（IF）（即Q 准备平面压印膜和相应的非压印膜作为对照样品，以评估传感器的检测能力。根据结果​​，由于其在结构化表面上的结合亲和力增强，与平面MIP传感器相比，MIP-QCM传感器具有增强的检测能力。印记因子（IF）（即Q 准备平面压印膜和相应的非压印膜作为对照样品，以评估传感器的检测能力。根据结果​​，由于其在结构化表面上的结合亲和力增强，与平面MIP传感器相比，MIP-QCM传感器具有增强的检测能力。印记因子（IF）（即Q_e，MIP / Q _e，NIP）表示对每个MIP膜的压印效果进行了比较评估，得出以下顺序：1.69（MIP平面）<2.21（MIP-5μm）<2.74（MIP-3μm） 。LOQ和LOD值分别为54.407和17.954 nM ^-1（MIP平面），24.624和8.126 nM ^-1（MIP-5μm），62.423和20.600 nM ^-1（MIP-3μm）。使用Freundlich等温模型评估异丙隆MIP膜的结合亲和力，在异丙隆水溶液中检测到的模板量在30到303 nM之间。此外，还在水溶液中还存在两种其他杀真菌剂：嘧啶酮和嘧啶酮的情况下研究了图案化的MIP膜对异丙隆的检测的选择性。