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Direct Catalytic Functionalization of Indazole Derivatives
Advanced Synthesis & Catalysis ( IF 4.4 ) Pub Date : 2020-05-27 , DOI: 10.1002/adsc.202000423
Sumit Ghosh 1 , Susmita Mondal 1 , Alakananda Hajra 1
Affiliation  

Indazoles are a very important class of N‐containing heterocycles with a wide range of biological and medicinal properties. The presence of different functionalities on indazole moieties enhances its biological activities. Hence, the preparation of indazole compounds bearing functional groups has gained a significant interest to the organic synthetic chemists. A large effort has been made to develop efficient and new methods for the functionalization of indazoles. Direct catalytic functionalization is a very powerful tool for facile synthesis of important indazole derivatives due to its straightforwardness. This review summarizes developments on direct functionalizations of indazoles published in the last two decades.

中文翻译:

吲唑衍生物的直接催化功能化

吲唑是一类非常重要的含氮杂环,具有广泛的生物学和医学特性。吲唑部分上不同功能的存在增强了其生物学活性。因此,带有官能团的吲唑化合物的制备已引起有机合成化学家的极大兴趣。为了开发吲唑官能化的有效和新方法,已经做出了巨大的努力。由于其直接性,直接催化功能化是重要合成吲唑衍生物的非常强大的工具。这篇综述总结了过去二十年来发表的吲唑直接功能化的进展。
更新日期:2020-05-27
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