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Recent Advances in Complex Coacervation Design from Macromolecular Assemblies and Emerging Applications.
Macromolecular Rapid Communications ( IF 4.2 ) Pub Date : 2020-05-20 , DOI: 10.1002/marc.202000149
Lili Zhou 1 , Huihui Shi 1 , Zibiao Li 2 , Chaobin He 1, 2
Affiliation  

Coacervation is a process during which a homogeneous aqueous solution undergoes liquid–liquid phase separation, giving rise to two immiscible liquid phases composed of a colloid‐rich coacervate phase in equilibrium with a colloid‐poor phase simultaneously. Recent attempts to develop complex coacervation from macromolecular self‐assemblies have diversified a large group of novel coacervate‐related materials with sophisticated properties and emerging applications. In this review, the most recent progress in the design strategies of macromolecular complex coacervation is discussed with respect to different key parameters, including macromolecular structure, mixing ratio, ionic strength, pH, and temperature, etc. Furthermore, the applications of these multiple‐functional coacervate materials, oriented toward advanced encapsulation, are further summarized into several active domains in wastewater treatment, protein purification, food formulation, underwater adhesives, drug delivery, and cellular mimics. Finally, perspectives and future challenges related to the further advancement of macromolecular complex coacervates are proposed.

中文翻译:

大分子组装和新兴应用中复杂凝聚层设计的最新进展。

凝聚是一个过程,在此过程中,均质的水溶液会经历液相-液相分离,从而产生两个不溶混的液相,该液相由富含胶体的凝聚相和平衡的贫胶相组成。最近从大分子自组装形成复杂凝聚的尝试使一大批新颖的凝聚层相关材料多样化,这些材料具有复杂的性能和新兴的应用。在这篇综述中,讨论了大分子复合物凝聚设计策略的最新进展,涉及不同的关键参数,包括大分子结构,混合比,离子强度,pH和温度等。此外,这些多元化学的应用面向高级封装的功能性凝聚层材料,在废水处理,蛋白质纯化,食品配方,水下粘合剂,药物递送和细胞模拟中,它们被进一步概括为几个活跃领域。最后,提出了与高分子复合凝聚层的进一步发展有关的观点和未来挑战。
更新日期:2020-05-20
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