Currently, due to the special functions and potential application values, rare sugars become the hot topic in carbohydrate fields. L-Ribulose, an isomer of L-ribose, is an expensive rare ketopentose. As an important precursor for other rare sugars and L-nucleoside analogue synthesis, L-ribulose attracts more and more attention in recent days. Compared with complicated chemical synthesis, the bioconversion method becomes a good alternative approach to L-ribulose production. Generally, the bioconversion of L-ribulose was linked with ribitol, L-arabinose, L-ribose, L-xylulose, and L-arabitol. Herein, an overview of recent advances in the metabolic pathway, chemical synthesis, bioproduction of L-ribulose, and the potential application of L-ribulose is reviewed in detail in this paper. KEY POINTS: 1. L-Ribulose is a rare sugar and the key precursor for L-ribose production. 2. L-Ribulose is the starting material for L-nucleoside derivative synthesis. 3. Chemical synthesis, bioproduction, and applications of L-ribulose are reviewed.

中文翻译：

---

L-核糖的性质，生产和应用方面的最新进展。

当前，由于特殊功能和潜在的应用价值，稀有糖成为碳水化合物领域的热门话题。L-核糖的异构体L-核糖是一种昂贵的稀有酮戊糖。作为其他稀有糖和L-核苷类似物合成的重要前体，L-核糖近年来受到越来越多的关注。与复杂的化学合成相比，生物转化方法成为生产L-核糖的一种很好的替代方法。通常，L-核糖的生物转化与核糖醇，L-阿拉伯糖，L-核糖，L-木酮糖和L-阿拉伯糖醇连接。本文中，对L-核糖的代谢途径，化学合成，生物生产以及L-核糖的潜在应用的最新进展进行了综述。要点：1。L-核糖是一种稀有糖，是生产L-核糖的关键前体。2. L-核糖是L-核苷衍生物合成的原料。3.综述了L-核糖的化学合成，生物生产和应用。