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Efficient Tosylation of Dihydroxybenzenes in a Two-Phase Water–Dichloromethane System
Theoretical and Experimental Chemistry ( IF 0.7 ) Pub Date : 2020-03-01 , DOI: 10.1007/s11237-020-09639-1 V. N. Anishchenko , A. N. Redko , V. I. Rybachenko
Theoretical and Experimental Chemistry ( IF 0.7 ) Pub Date : 2020-03-01 , DOI: 10.1007/s11237-020-09639-1 V. N. Anishchenko , A. N. Redko , V. I. Rybachenko
The effect of the structure of the catalyst and the type of base on the reaction rate and product yield of the tosylation of dihydroxybenzenes in a two-phase water–dichloromethane system in the presence of pyridine N-oxide derivatives was demonstrated. It was found that with 4-dimethylaminopyridine N-oxide and potassium carbonate it is possible to obtain dihydroxybenzene tosylates with yields of more than 90%.
中文翻译:
在两相水-二氯甲烷系统中二羟基苯的有效甲苯磺酰化
证明了催化剂的结构和碱的类型对在吡啶 N-氧化物衍生物存在下在两相水 - 二氯甲烷体系中二羟基苯甲苯磺酰化反应速率和产物产率的影响。发现使用4-二甲氨基吡啶N-氧化物和碳酸钾可以以超过90%的产率获得二羟基苯甲苯磺酸盐。
更新日期:2020-03-01
中文翻译:
在两相水-二氯甲烷系统中二羟基苯的有效甲苯磺酰化
证明了催化剂的结构和碱的类型对在吡啶 N-氧化物衍生物存在下在两相水 - 二氯甲烷体系中二羟基苯甲苯磺酰化反应速率和产物产率的影响。发现使用4-二甲氨基吡啶N-氧化物和碳酸钾可以以超过90%的产率获得二羟基苯甲苯磺酸盐。