Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
BF3·OEt2-Catalyzed Aldol Condensation of Steroid Sapogenins and 2-Oxoacids: A Single Step Conversion of Steroid Spiroketals into Branched α,β-Unsaturated Spirolactones
Synthesis ( IF 2.2 ) Pub Date : 2020-04-21 , DOI: 10.1055/s-0040-1708018 Martin A. Iglesias-Arteaga 1 , Juan E. Hernández-Martínez
Synthesis ( IF 2.2 ) Pub Date : 2020-04-21 , DOI: 10.1055/s-0040-1708018 Martin A. Iglesias-Arteaga 1 , Juan E. Hernández-Martínez
Affiliation
|
BF3·OEt2-catalyzed aldol reaction of steroid sapogenins with glyoxylic acid or pyruvic acid led to compounds in which the novel spirocyclic side chain bears an α,β-unsaturated lactone. The structures of the new spirolactones were established with the aid of combined 1D and 2D NMR techniques. A plausible mechanism is described.
中文翻译：
BF3·OEt2催化类固醇皂甙元和2-含氧酸的醛醇缩合：类固醇螺缩酮一步一步转化为支链α，β-不饱和螺内酯
BF 3 ·OEt 2催化类固醇皂苷元与乙醛酸或丙酮酸的醛醇缩合反应生成了新型螺环侧链带有α，β-不饱和内酯的化合物。借助1D和2D NMR技术，确定了新的螺内酯的结构。描述了一种合理的机制。
更新日期：2020-04-21
中文翻译：
BF3·OEt2催化类固醇皂甙元和2-含氧酸的醛醇缩合：类固醇螺缩酮一步一步转化为支链α，β-不饱和螺内酯
BF 3 ·OEt 2催化类固醇皂苷元与乙醛酸或丙酮酸的醛醇缩合反应生成了新型螺环侧链带有α，β-不饱和内酯的化合物。借助1D和2D NMR技术，确定了新的螺内酯的结构。描述了一种合理的机制。
京公网安备 11010802027423号