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Characterization of gelatin hydrogels derived from different animal sources
Materials Letters ( IF 2.7 ) Pub Date : 2020-08-01 , DOI: 10.1016/j.matlet.2020.127865
Laura Michelini , Luca Probo , Silvia Farè , Nicola Contessi Negrini
Materials Letters ( IF 2.7 ) Pub Date : 2020-08-01 , DOI: 10.1016/j.matlet.2020.127865
Laura Michelini , Luca Probo , Silvia Farè , Nicola Contessi Negrini
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Abstract Gelatin hydrogels are a valid alternative to produce scaffolds, wound dressings, and drug delivery systems. However, the animal source from which collagen is extracted to obtain gelatin and its treatment are often underestimated despite they can influence the properties of the obtained gelatin hydrogels. Here, three gelatin powders derived from different animal sources (i.e., porcine, bovine and cold water fish) are chemically crosslinked by two reactions and their physico-mechanical properties investigated. The non-cytotoxic hydrogels swelled differently in water (i.e., porcine > fish > bovine), which in turn influenced the mechanical properties of the obtained hydrogels, highlighting the importance of properly selecting the gelatin source when preparing gelatin hydrogels.
中文翻译:
来自不同动物来源的明胶水凝胶的表征
摘要 明胶水凝胶是生产支架、伤口敷料和药物输送系统的有效替代品。然而,提取胶原蛋白以获得明胶的动物来源及其处理往往被低估,尽管它们会影响所获得的明胶水凝胶的性质。在这里,来自不同动物来源(即猪、牛和冷水鱼)的三种明胶粉通过两个反应进行化学交联,并研究了它们的物理机械特性。非细胞毒性水凝胶在水中的膨胀不同(即猪>鱼>牛),这反过来影响了所得水凝胶的机械性能,突出了在制备明胶水凝胶时正确选择明胶来源的重要性。
更新日期:2020-08-01
中文翻译:
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来自不同动物来源的明胶水凝胶的表征
摘要 明胶水凝胶是生产支架、伤口敷料和药物输送系统的有效替代品。然而,提取胶原蛋白以获得明胶的动物来源及其处理往往被低估,尽管它们会影响所获得的明胶水凝胶的性质。在这里,来自不同动物来源(即猪、牛和冷水鱼)的三种明胶粉通过两个反应进行化学交联,并研究了它们的物理机械特性。非细胞毒性水凝胶在水中的膨胀不同(即猪>鱼>牛),这反过来影响了所得水凝胶的机械性能,突出了在制备明胶水凝胶时正确选择明胶来源的重要性。