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Skipping adolescence to become super-inflammatory monocytes.
Nature Immunology ( IF 27.7 ) Pub Date : 2020-05-01 , DOI: 10.1038/s41590-020-0652-2
Burkhard Becher 1 , Donatella De Feo 1 , Ana Amorim 1 , Melanie Greter 1
Affiliation  

Single-cell RNA-sequencing of myeloid cells during neuroinflammation identifies a new population of pathogenic Cxcl10-expressing phagocytes, which develop independently of Ly6Chi monocytes but derive from early myeloid precursors shaped by the inflamed tissue microenvironment.

中文翻译:

跳过青春期成为超炎性单核细胞。

在神经炎症过程中,髓样细胞的单细胞RNA测序确定了新的致病性Cxcl10表达吞噬细胞群,其独立于Ly6Chi单核细胞发育,但源自受炎症组织微环境影响的早期髓样前体。
更新日期:2020-04-24
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