Copper-catalyzed azide–alkyne cycloaddition is a useful tool for the synthesis of both 1,2,3-triazoles and 5-iodo-1H-1,2,3-triazoles starting from either terminal alkynes or iodoalkynes. 5-Iodotriazoles have been recognized as very useful building blocks for the synthesis of diverse 1,4,5-trisubstituted 1,2,3-triazoles. Synthetic application of 5-iodo-1,2,3-triazoles through the creation of a new C–C, C–heteroatom, or C–D(T) bond along with the application areas of both iodotriazoles and products of their modification including radiolabeled compounds are discussed.

中文翻译：

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5-碘-1H-1,2,3-三唑类化合物

铜催化的叠氮化物-炔烃环加成反应是从末端炔烃或碘炔烃开始合成1,2,3-三唑和5-碘-1 H -1,2,3-三唑的有用工具。5-碘三唑已被认为是用于合成各种1,4,5-三取代的1,2,3-三唑的非常有用的结构单元。通过创建新的C–C，C–杂原子或C–D（T）键以及碘代三唑及其改性产物的应用领域，对5-碘-1,2,3-三唑进行合成应用讨论了放射性标记的化合物。