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Review of the effects of vitexin in oxidative stress-related diseases.
Food Science & Nutrition ( IF 3.5 ) Pub Date : 2020-04-14 , DOI: 10.1002/fsn3.1567
Fatemeh Babaei 1 , Armita Moafizad 2 , Zahra Darvishvand 2 , Mohammadreza Mirzababaei 3 , Hossein Hosseinzadeh 4, 5 , Marjan Nassiri-Asl 6
Affiliation  

Vitexin is an apigenin flavone glycoside found in food and medicinal plants. It has a variety of pharmacological effects, including antioxidant, anti‐inflammatory, anticancer, antinociceptive, and neuroprotective effects. This review study summarizes all the protective effects of vitexin as an antioxidant against reactive oxygen species, lipid peroxidation, and other oxidative damages in a variety of oxidative stress‐related diseases, including seizure, memory impairment, cerebral ischemia, neurotoxicity, myocardial and respiratory injury, and metabolic dysfunction, with possible molecular and cellular mechanisms. This review describes any activation or inhibition of the signaling pathways that depend on the antioxidant activity of vitexin. More basic research is needed on the antioxidative effects of vitexin in vivo, and carrying out clinical trials for the treatment of oxidative stress‐related diseases is also recommended.

中文翻译:

葡萄黄素在氧化应激相关疾病中的作用综述。

Vitexin是一种在食品和药用植物中发现的芹菜素黄酮苷。它具有多种药理作用,包括抗氧化剂,抗炎,抗癌,抗伤害感受和神经保护作用。这篇综述性研究总结了vitexin作为抗氧化剂的抗氧化活性物质,脂质过氧化以及其他各种与氧化应激相关疾病的其他氧化损伤的保护作用,包括癫痫发作,记忆力减退,脑缺血,神经毒性,心肌和呼吸系统损伤和代谢功能障碍,可能具有分子和细胞机制。这篇综述描述了依赖于vitexin的抗氧化活性的信号通路的任何激活或抑制。关于vitexin在体内的抗氧化作用,需要更多的基础研究,
更新日期:2020-04-14
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