Review of the effects of vitexin in oxidative stress-related diseases.,Food Science & Nutrition

当前位置： X-MOL 学术 › Food Sci. Nutr. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Review of the effects of vitexin in oxidative stress-related diseases.
Food Science & Nutrition ( IF 3.5 ) Pub Date : 2020-04-14 , DOI: 10.1002/fsn3.1567
Fatemeh Babaei ₁ , Armita Moafizad ₂ , Zahra Darvishvand ₂ , Mohammadreza Mirzababaei ₃ , Hossein Hosseinzadeh _{4,

5} , Marjan Nassiri-Asl ₆

Affiliation

Vitexin is an apigenin flavone glycoside found in food and medicinal plants. It has a variety of pharmacological effects, including antioxidant, anti‐inflammatory, anticancer, antinociceptive, and neuroprotective effects. This review study summarizes all the protective effects of vitexin as an antioxidant against reactive oxygen species, lipid peroxidation, and other oxidative damages in a variety of oxidative stress‐related diseases, including seizure, memory impairment, cerebral ischemia, neurotoxicity, myocardial and respiratory injury, and metabolic dysfunction, with possible molecular and cellular mechanisms. This review describes any activation or inhibition of the signaling pathways that depend on the antioxidant activity of vitexin. More basic research is needed on the antioxidative effects of vitexin in vivo, and carrying out clinical trials for the treatment of oxidative stress‐related diseases is also recommended.

中文翻译：

牡荆素在氧化应激相关疾病中的作用综述。

牡荆素是一种芹菜素黄酮糖苷，存在于食品和药用植物中。它具有多种药理作用，包括抗氧化、抗炎、抗癌、镇痛和神经保护作用。本综述研究总结了牡荆素作为抗氧化剂对活性氧、脂质过氧化和其他氧化损伤在多种氧化应激相关疾病中的保护作用，包括癫痫、记忆障碍、脑缺血、神经毒性、心肌和呼吸损伤和代谢功能障碍，可能具有分子和细胞机制。这篇综述描述了依赖于牡荆素抗氧化活性的信号通路的激活或抑制。牡荆素的体内抗氧化作用需要更多的基础研究，并建议开展治疗氧化应激相关疾病的临床试验。

更新日期：2020-04-14

点击分享查看原文

点击收藏

公开下载

阅读更多本刊新发论文本刊介绍/投稿指南