Circular Nucleic Acids: Discovery, Functions and Applications.,ChemBioChem

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Circular Nucleic Acids: Discovery, Functions and Applications.
ChemBioChem ( IF 2.6 ) Pub Date : 2020-03-16 , DOI: 10.1002/cbic.202000003
Jiuxing Li ₁ , Mostafa Mohammed-Elsabagh ₁ , Freeman Paczkowski ₁ , Yingfu Li ₁

Affiliation

Going round again : Owing to their unique topological structures, biological stability, and ease of coupling with rolling circle amplification for the synthesis of a long, single‐stranded product with tandem repeats, circular nucleic acids have been extensively applied in diagnosis, therapy, and bio‐nanotechnology. Progress in the discovery, construction, and applications of circular nucleic acids is reviewed.