A mixture of taxols was prepared from 10-deacetyl-7-xylosyltaxanes by three-step reactions: redox, acetylation, and deacetylation. The mixture was separated by column chromatography on silica gel to afford Taxol, Taxol B (Cephalomannine) and Taxol C. The mixture of Taxol B and Taxol C was converted to Docetaxel by Schwartz's reagent. The structures of Taxol and Docetaxel were characterized by HPLC, 1 H-NMR, 13 C-NMR and MS. This synthetic process has expanded the source of biomass for the chemical semi-synthesis of Taxol and Docetaxel, reduced the production costs, and increased the biomass resource of taxanes.

中文翻译：

---

使用10-脱乙酰基-7-木糖基紫杉烷类化合物合成紫杉醇和多西紫杉醇。

由三步反应：氧化还原，乙酰化和脱乙酰化，由10-脱乙酰基-7-木糖基紫杉烷制备紫杉醇的混合物。通过硅胶上的柱色谱分离混合物，得到紫杉醇，紫杉醇B（头孢氨苄）和紫杉醇C。紫杉醇B和紫杉醇C的混合物通过施瓦茨试剂转化为多西紫杉醇。紫杉醇和多西他赛的结构通过HPLC，1 H-NMR，13 C-NMR和MS表征。该合成方法拓宽了紫杉醇和多西紫杉醇化学半合成的生物质来源，降低了生产成本，并增加了紫杉烷类生物质资源。