Abstract

A catalytic, high yielding and scalable procedure for the synthesis of 9H-carbazole-3,6-dicarbonitrile has been developed. Subsequent hydrolysis of the dinitrile in the presence of a catalytic copper species (i.e., CuI) yields 9H-carbazole-3,6-dicarboxylic acid. Both compounds are versatile and fine-tunable organic building blocks and therefore offer potential in material science, medicinal and supramolecular chemistry.

A catalytic, high yielding and scalable procedure for the synthesis of 9H-carbazole-3,6-dicarbonitrile has been developed. Subsequent hydrolysis of the dinitrile in the presence of a catalytic copper species (i.e., CuI) yields 9H-carbazole-3,6-dicarboxylic acid. Both compounds are versatile and fine-tunable organic building blocks and therefore offer potential in material science, medicinal and supramolecular chemistry.

中文翻译：

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9H-咔唑-3,6-二腈和9H-咔唑-3,6-二羧酸的便捷制备

摘要

已开发出催化，高产率且可扩展的合成9 H-咔唑-3,6-二腈的方法。在催化性铜物质（即CuI）存在下，二腈的后续水解产生9 H-咔唑-3,6-二羧酸。两种化合物都是通用且可微调的有机组成部分，因此在材料科学，药物和超分子化学方面具有潜力。

已开发出催化，高产率且可扩展的合成9 H-咔唑-3,6-二腈的方法。在催化性铜物质（即CuI）存在下，二腈的后续水解产生9 H-咔唑-3,6-二羧酸。两种化合物都是通用且可微调的有机组成部分，因此在材料科学，药物和超分子化学方面具有潜力。