A method amenable to the multigram-scale preparation of 4-chloropyridine-2,6-dicarbonyl dichloride is described. The key transformation is the deoxygenative chlorination of the pyridine N-oxide with oxalyl choride.

4-chloropyridine-2,6-dicarbonyl dichloride - supramolecular chemistry - deoxygenative chlorination - carboxylic acid chlorides - nitrogen heterocycles

中文翻译：

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便利的Multigram合成4-氯吡啶-2,6-二羰基二氯化物

描述了适合于数克规模制备4-氯吡啶-2，6-二羰基二氯化物的方法。关键的转化是将吡啶N-氧化物与草酰氯进行脱氧氯化反应。

4-氯吡啶-2,6-二羰基二氯化物-超分子化学-脱氧氯化-羧酸氯化物-氮杂环