A simple synthesis of 5-(trifluoromethyl)cyclohexane-1,2,3-trione is demonstrated in one step, by reacting 5-(trifluoromethyl)cyclohexane-1,3-dione with cerium(IV)ammonium nitrate (CAN) in methanol. The compound represents a highly functionalized oxygen-rich reactive intermediate for the synthesis of organic and heterocyclic compounds containing fluorine.

中文翻译：

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5-（三氟甲基）环己烷-1,2,3-三酮（cVTC）的合成：新的三氟甲基构件

通过使5-（三氟甲基）环己烷-1,3-二酮与硝酸铈（IV）铵（CAN）在甲醇中反应，一步展示了5-（三氟甲基）环己烷-1,2,3-三酮的简单合成。该化合物代表高度官能化的富氧反应性中间体，用于合成含氟的有机和杂环化合物。