2,4,6-Tribromophenol is the most widely produced brominated phenol. In the present review, we summarize studies dealing with this substance from an environmental point of view. We cover concentrations in the abiotic and biotic environment including humans, toxicokinetics as well as toxicodynamics, and show gaps of the current knowledge about this chemical.

2,4,6-Tribomophenol occurs as an intermediate during the synthesis of brominated flame retardants and it similarly represents a degradation product of these substances. Moreover, it is used as a pesticide but also occurs as a natural product of some aquatic organisms. Due to its many sources, 2,4,6-tribromophenol is ubiquitously found in the environment. Nevertheless, not much is known about its toxicokinetics and toxicodynamics. It is also unclear which role the structural isomer 2,4,5-tribromophenol and several degradation products such as 2,4-dibromophenol play in the environment. Due to new flame retardants that enter the market and can degrade to 2,4,6-tribromophenol, this compound will remain relevant in future years – not only in aquatic matrices, but also in house dust and foodstuff, which are an important exposure route for humans.

2,4,6-三溴苯酚是最广泛生产的溴化苯酚。在本综述中，我们从环境角度总结了处理该物质的研究。我们涵盖了非生物和生物环境中的浓度，包括人类，毒物动力学以及毒物动力学，并显示了有关该化学物质的最新知识的差距。

2,4,6-三苯酚是溴化阻燃剂合成过程中的中间体，它类似地代表这些物质的降解产物。此外，它被用作杀虫剂，但也作为某些水生生物的天然产物而存在。由于其来源众多，因此在环境中普遍存在2,4,6-三溴苯酚。然而，对其毒性动力学和毒动力学知之甚少。还不清楚结构异构体2,4,5-三溴苯酚和几种降解产物（例如2,4-二溴苯酚）在环境中起什么作用。由于新的阻燃剂已经进入市场，并且可以降解为2,4,6-三溴苯酚，因此该化合物在未来几年中仍将保持重要地位-不仅在水基质中，而且在房屋粉尘和食品中也是重要的暴露途径对于人类。