市售电子烟油中大麻酚含量的量化及其热稳定性和光稳定性的研究。,Scientific Reports

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市售电子烟油中大麻酚含量的量化及其热稳定性和光稳定性的研究。
Scientific Reports ( IF 3.8 ) Pub Date : 2020-02-28 , DOI: 10.1038/s41598-020-60477-6
Carlo Mazzetti ₁ , Emanuele Ferri ₂ , Monica Pozzi ₂ , Massimo Labra ₁

Affiliation

大麻二酚 (CBD) 已成为许多市场上蓬勃发展的产品的流行语。科学界和一些当局最近对这些产品的质量提出了担忧。特别是，电子烟液体中大麻二酚的标签和实际含量之间的差异似乎正在成为一个主要问题。此外，迄今为止，尚未对此类产品在储存时的化学稳定性进行过研究。这项工作的目的是研究 13 种含有 CBD 的商业电子烟液的标签准确性以及不同储存条件对其质量的影响。结果表明，只有 38% 的样本被标记在与其标签相差 ±10% 的范围内。稳定性测试表明，当样品在 37°C 下储存 30 天时，CBD 的降解最大，平均值高达 20%。光的影响较低，但仍然显着，30 天后的平均降解率高达 15%。总之，我们认为卫生当局应该更严格地监管和控制这个市场，以保护客户及其健康。此外，我们的稳定性测试表明，如果在最佳储存条件下提供明确的指示，则这些产品的质量可以得到大部分保留。

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Quantification of the content of cannabinol in commercially available e-liquids and studies on their thermal and photo-stability.

Cannabidiol (CBD) has become a buzzword in many products that have bloomed on the market. The scientific community and some authorities have recently raised concerns on the quality of these products. In particular, the discrepancy between the labelled and the real content of cannabidiol in liquids for e-cigarettes seems to be emerging as a major issue. Furthermore, to-date no studies have been carried out on the chemical stability upon storage of these type of products. The aim of this work was to investigate the accuracy in labelling of thirteen commercially e-liquids containing CBD and the effects of different storage conditions on their quality. The results showed that only 38% of samples were labelled within a ±10% variance from their labels. Stability tests showed a maximum degradation of CBD when samples were stored at 37 °C for 30 days with average values up to 20%. The effect of light was lower but still significant with averages values up to 15% degradation after 30 days. In conclusion, we believe that health authorities should regulate and control this market more stringently to protect customers and their health. Furthermore, our stability tests have shown that if clear indications are provided on the best storage conditions, the quality of these products can be mostly preserved.

更新日期：2020-02-28

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