Department of Gastroenterology; The Third Medical Centre; Chinese PLA General Hospital; Beijing 100039 China
Department of Gastroenterology; Anhui No.2 Provincial People's Hospital; Hefei 230041 China
CAS Key Laboratory of Molecular Imaging; Beijing Key Laboratory of Molecular Imaging; The State Key Laboratory of Management and Control for Complex Systems; Institute of Automation; Chinese Academy of Sciences; University of Chinese Academy of Sciences; Beijing 100190 China
School of Life Science and Technology; Xidian University; Xi'an 710071 China
Department of Nuclear Medicine; Chinese PLA General Hospital; Beijing 100853 China
School of Information Sciences and Technology; Northwest University; Xi'an 710127 China
Aiming to achieve precise tumor surgery, Zhenhua Hu, Haifeng Liu, Jie Tian, and co‐workers develop a multimodality in vivo imaging strategy combining nuclear imaging, optical imaging and microscopy. High performance is achieved in tumor detection and surgical navigation using clinically approved agents. This strategy based on Cherenkov excited fluorescent imaging demonstrates high clinical translational potential and opens a new direction for surgical navigation research.