In article 1801531, Rong Fan and co‐workers examine the dynamics of brain tumor cells in a microvasculature‐on‐a‐chip system. Tumor cells residing in the perivascular zone show various degrees of co‐localization with microvessels across ten glioblastoma patients. Single‐cell transcriptome sequencing (21 750 single cells) reveals that brain tumor cells with high expression of PDGFRA preferentially localize in the perivascular niche.

中文翻译：

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芯片上器官：芯片上微脉管系统中人胶质母细胞瘤细胞的体外动力学与肿瘤异质性和亚型相关（Adv。Sci。8/2019）

范凡和他的同事在文章1801531中研究了微血管芯片系统中脑肿瘤细胞的动力学。在十名胶质母细胞瘤患者中，位于血管周区域的肿瘤细胞与微血管显示不同程度的共定位。单细胞转录组测序（21 750个单细胞）显示，PDGFRA高表达的脑肿瘤细胞优先定位在血管周生境中。