We report a stepwise preparation of triple alkylated or arylated tertiary amines, starting from commercially available tris(2-cyanoethyl)amine using three successive reaction sequences involving a selective oxidation (formation of an N-oxide followed by a Cope elimination) leading to an intermediate hydroxylamine, a benzoylation, and a cobalt-catalyzed electrophilic amination with organozinc halides.

中文翻译：

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由三（2-氰乙基）胺经三步钴催化的亲电子胺与卤化有机锌的合成，制备叔胺。

我们报告了逐步烷基三芳基化或芳基化叔胺的制备，从市售的三（2-氰基乙基）胺开始，使用三个连续的反应序列，涉及选择性氧化（形成N-氧化物，然后进行Cope消除），导致形成中间体羟胺，苯甲酰化反应以及钴与有机卤化锌的亲电子胺化反应。