An efficient and practical synthesis of benzothiazine by visible-light-mediated free radical reaction has been developed. This protocol provides a new, facile, eco-friendly strategy to construct benzothiazine and quinoxaline derivatives via formation of C–S and C–N bonds under metal-free condition. This synthesis has been performed under visible light illumination in aqueous ethanol at room temperature using aromatic aldehyde, o-aminothiophenol and isocyanide as reactants.Graphical Abstract

中文翻译：

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4H-苯并[1,4]噻嗪-2-胺和3,4-二氢喹喔啉-2-胺的可见光介导合成：形成C-S、C-N键的有效且无金属途径

已经开发出一种通过可见光介导的自由基反应有效且实用的苯并噻嗪合成方法。该协议提供了一种新的、简便的、环保的策略，通过在无金属条件下形成 C-S 和 C-N 键来构建苯并噻嗪和喹喔啉衍生物。该合成是在室温下在乙醇水溶液中的可见光照射下使用芳香醛、邻氨基苯硫酚和异氰化物作为反应物进行的。