Alkylation of 2-sulfanylpyridine-3-carboxylic acid with 3-bromo-1-propyne proceeds with the formation of 2-(prop-2-yn-1-ylsulfanyl)-pyridine-3-carboxylic acid and prop-2-yn-1-yl 2-(prop-2-yn-1-ylsulfanyl)pyridine-3-carboxylate, which react with bromine and iodine to form 2,3-dihydro[1,3]thiazolo[3,2-a]pyridinium systems.

中文翻译：

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2-巯基烟酸炔丙基衍生物的合成和卤代化

2-磺酰胺基吡啶-3-羧酸与3-溴-1-丙炔的烷基化反应继而形成了2-（prop-2-yn-1-ylulfanyl）-吡啶-3-羧酸和prop-2-yn- 1-（2--2-丙-2-炔-1-基硫烷基）吡啶-3-羧酸酯，与溴和碘反应形成2,3-二氢[1,3]噻唑并[3,2- a ]吡啶鎓体系。