Abstract

Novel chromonyl phosphonic acid 3, diethyl chromonyl phosphonate 4, and diethyl chromonyl pyridinyl phosphonate 5 were obtained from treatment of 2-cyano-3-(4-oxo-4H-chromen-3-yl) prop-2-enamide (2) with phosphorous acid and its diesters. Also, an efficient route to functionalized phosphorus heterocycles such as 1,2,3-diazaphosphinane, 1,2,3-thiazaphosphinine and 1,2-azaphosphole bearing a chromone ring was achieved via reaction of compound 2 with some phosphorus sulfides and phosphorus tribromide. A key part of the reaction mechanisms is discussed. Structures of the new synthesized products were established on the basis of spectral data (IR, ESI-MS, ¹H-, ¹³C and ³¹P-NMR spectra).

Graphical Abstract

An efficient route to functionalized phosphorus heterocycles such as 1,2,3-diazaphosphinane, 1,2,3-thiazaphosphinine and 1,2-azaphosphole bearing a chromone ring was achieved via reaction of 2-cyano-3-(4-oxo-4H-chromen-3-yl)prop-2-enamide with some phosphorus sulfides and phosphorus tribromide.

中文翻译：

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2-氰基-3-（4-oxo-4 H -chromen-3-yl）prop-2-enamide与某些磷试剂的反应：一些新型膦酸二乙酯，1,2,3-二氮膦膦，1,2的合成带有色酮环的，3-噻唑膦和1,2-氮唑

摘要

通过处理2-氰基-3-（4-氧代-4 H-铬-3-基）丙-2-烯酰胺（2）获得了新型的苯甲酰基膦酸3，苯二甲酰基膦酸膦酸4和苯二甲基吡啶基膦酸膦酸5。亚磷酸及其二酯。而且，通过化合物2与一些硫化磷和三溴化磷的反应，获得了通往官能化磷杂环（例如1,2,3-二氮杂膦烷，1,2,3-硫杂氮杂膦和带有色酮环的1,2-氮杂磷腈）的有效途径。。讨论了反应机理的关键部分。根据光谱数据（IR，ESI-MS，¹ H-，¹³ C和³¹ P-NMR光谱）。

图形概要

通过2-氰基-3-（4-氧代-）-的反应，可以得到一种有效的途径来合成功能化的磷杂环化合物，例如1,2,3-二氮杂膦烷，1,2,3-硫杂氮杂膦和带有色酮环的1,2-氮杂磷腈。 4 H-铬-3-基）丙-2-烯酰胺与一些硫化磷和三溴化磷。