Introduction

The perinatal period represents a time of significant life changes associated with increases in sleep difficulties, depression, and potentially impaired quality of life (QoL). Associations between QoL and sleep among women with perinatal depression are poorly understood, and changes in QoL across the perinatal period have received little attention.

Methods

Participants were the treatment-as-usual group (n = 23) from a clinical trial testing an intervention for perinatal mood disorders. They completed the WHOQOL-Bref, had depression assessed with the HAM-D-17, and wore wrist actigraphs to estimate sleep for 1 week during third trimester and at 6 weeks postpartum.

Results

Higher education level was associated with better environmental QoL during pregnancy (p = .044) and presence of older children was associated with worse social QoL postpartum (p = .045). Psychological health QoL worsened (p = .014) across the perinatal period. Total sleep time (p = .001) and sleep efficiency (p = .008) decreased from third trimester to postpartum week 6, but sleep measures were not associated with QoL at either time point. Depressive symptoms decreased from pregnancy to postpartum week 6 and were inversely associated with postpartum physical and social QoL (p = .031 and .048).

Discussion

Factors contributing to self-rated QoL are variable across multiple domains during the perinatal period. QoL among our participants was lower than population norms. In our sample of women with depression and/or anxiety, QoL was related to postpartum depressive symptoms, but not to objectively measured sleep quality, quantity, or timing. Links between QoL and sleep may be inherently complex in perinatal women.

中文翻译：

---

患有情绪障碍的妇女整个围产期生活和睡眠质量的变化。

介绍

围产期代表着生活显着变化的时间，与睡眠困难，抑郁和可能的生活质量（QoL）升高相关。对围生期抑郁症妇女的QoL与睡眠之间的关联了解甚少，并且整个围产期QoL的变化很少受到关注。

方法

参加者为常规治疗组（n  = 23），来自临床试验，对围产期情绪障碍进行干预。他们完成了WHOQOL-Bref，通过HAM-D-17进行了抑郁评估，并戴了腕部活动记录仪以估计妊娠中期和产后6周的睡眠时间。

结果

较高的教育水平与怀孕期间更好的环境QoL有关（p  = .044），年龄较大的孩子的存在与产后社会QoL恶化有关（p  = .045）。 围产期的心理健康QoL恶化（p = .014）。 从孕中期到产后第6周，总睡眠时间（p  = .001）和睡眠效率（p = .008）下降，但是在任何一个时间点，睡眠指标均与QoL无关。从怀孕到产后第6周，抑郁症状有所减轻，并且与产后身体和社会生活质量呈负相关（p  = .031和.048）。

讨论区

在围产期，影响自我QoL的因素在多个领域中均存在差异。我们参与者的生活质量低于人群标准。在我们的抑郁症和/或焦虑症妇女样本中，QoL与产后抑郁症状有关，但与客观测量睡眠质量，数量或时间无关。围产期妇女的生活质量和睡眠之间的联系可能固有地很复杂。