The authors describe a process that may eventually reduce the risk of scar formation after glaucoma surgery. For this, a thin hydrogel coating is photochemically generated and linked to the sclera surface at the surgical site. This coating is generated from a photoreactive prepolymer containing anthraquinone groups, which is administered as a thin pad to the sclera surface. Short UV irradiation leads to a reaction of the photogroups with neighboring chains via C-H insertion crosslinking, thus transforming the precursor polymer into a hydrogel. Simultaneously, a reaction between the photogroups and the underlying sclera tissue occurs, so that the hydrogel patch becomes covalently linked to the tissue. The authors show that the resulting thin coating is strongly cell repellent and hinders tenon fibroblasts to form tenon tissue at the site of the coating and is suitable for inclusion into a surgical procedure.

中文翻译：

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在青光眼手术后，通过PDMAA聚合物防止眼球对巩膜的粘附，以改善结果。

作者描述了一种可以最终减少青光眼手术后形成疤痕的风险的过程。为此，通过光化学方法产生薄的水凝胶涂层，并将其连接到手术部位的巩膜表面。该涂层由含有蒽醌基团的光反应性预聚物生成，该涂层以薄垫的形式施用于巩膜表面。短的紫外线照射导致光基团通过CH插入交联反应与相邻链反应，从而将前体聚合物转化为水凝胶。同时，在光基团和下面的巩膜组织之间发生反应，使得水凝胶贴片与组织共价连接。